Description
Product Characteristics: Recombinant Pyruvate Dehydrogenase Kinase Isozyme 2 (PDK2), Prokaryotic expression, Leu155-Trp379 (Accession # Q9JK42), N-terminal His Tag
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Target Information: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]